| ORIGINAL ARTICLE |
|
| Year : 2022 | Volume
: 14
| Issue : 2 | Page : 49-54 |
|
|
Targeted nutritional supplementation for telogen effluvium: Multicenter study on efficacy of a hydrolyzed collagen, vitamin., and mineral-based induction and maintenance treatment
Eva Maria Arias1, Nuria Floriach1, Gerardo Moreno-Arias2, Alejandro Camps2, Salvador Arias3, Ralph Michel Trüeb4
1 R&D Department, Laboratorio Genové, Sant Llorenç d'Hortons, Spain
2 Department of Dermatology, Centro Médico Teknon, Barcelona, Spain
3 Department of Dermatology, Hospital Universitario Virgen de las Nieves, Granada, Spain
4 Centre for Dermatology and Hair Diseases Professor Trüeb, Zurich-Wallisellen, Switzerland
Correspondence Address:
Ralph Michel Trüeb
Center for Dermatology and Hair Diseases Professor Trüeb, Bahnhofplatz 1A, CH-8304 Wallisellen
Switzerland
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijt.ijt_57_21
|
|
|
Background: The condition of the hair is closely related to the nutritional state. Normal supply, uptake, and transport of nutrients are of fundamental importance in tissues with a high biosynthetic activity such as the hair follicle. Objective: The objective of the study was to evaluate the efficacy of a nutritional-based induction and maintenance treatment for telogen effluvium formulated with a combination of hydrolyzed collagen, amino acids, vitamins, and minerals. Patients and Methods: The clinical studies were conducted with each nutritional treatment individually, and both in sequential combination. Anagen/telogen ratio, hair density, and tolerability of treatment were assessed at baseline, 4 weeks of induction therapy, and another 12 weeks of maintenance treatment. Trichogram results showed a significant improvement of the anagen/telogen ratio between baseline and final visit at 16 weeks, with an increase of hair in anagen and a reduction of hair in telogen. Furthermore, a significant increase was observed in hair density. The effect size of the combination treatment was higher than that of each of the two products used separately as monotherapy. Conclusions: The study results provide a proof of concept for targeted nutritional supplementation for the treatment of telogen effluvium, with a special emphasis on the role of collagen, besides specific amino acids, vitamins, and minerals.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
