|Year : 2020 | Volume
| Issue : 1 | Page : 41-42
Calcifying epithelioma of malherbe of the eyebrow
Manpreet Singh, Manjula Sharma, Manpreet Kaur, Pankaj Gupta
Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India
|Date of Submission||19-Feb-2020|
|Date of Decision||17-Mar-2020|
|Date of Acceptance||23-Mar-2020|
|Date of Web Publication||09-Apr-2020|
Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Singh M, Sharma M, Kaur M, Gupta P. Calcifying epithelioma of malherbe of the eyebrow. Int J Trichol 2020;12:41-2
A 31-year-old female had a painless, slow-growing lesion over the right sub-brow region of 3 months duration. Examination showed a localized, subcutaneous, yellowish mass (8 mm × 7 mm) with bluish-black peripheral discoloration [Figure 1]. The mass was firm-to-hard and adherent to overlying skin. The rest of the ophthalmic examination was within the normal limits. A working diagnosis of epithelial inclusion cyst and sarcoid nodule was kept, and an excisional biopsy was performed. The overlying adherent skin was removed with the mass followed by direct closure of undermined normal skin margins. Histopathology showed squamous cells arranged in clusters and nodules containing shadow cells or ghost cells (acellular eosinophilic material) in the dermis layer with unremarkable epidermis [Figure 2]. A foreign-body giant cell reaction was also noted. There were no basaloid cells, and the Congo-red stain did not show any congophilic material. The final diagnosis of eyelid pilomatrixomawas established, and the patient showed she is doing well at 1-year follow-up.
|Figure 1: The eyebrow skin lesion showing bluish-black peripheral discoloration|
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|Figure 2: Basaloid cells and shadow cells arranged in clusters with giant cell inflammatory reaction (H and E, ×40)|
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Eyelid pilomatrixoma or pilomatricoma, aka calcifying epithelioma of Malherbe, is a rare benign tumor originating from the hair-root matrix cells. The majority of cases occur in children with a female preponderance. It presents as a solitary, painless lesion that may show rapid progression, especially after trauma. This benign tumor consists of basaloid and shadow cells in combination with inflammation (foreign-body giant cells), calcification, and ossification.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
The authors would like to thank Prof. Usha Singh, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, for her teachings and support.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Chen HC, Brownstein S, Tang T, Grynspan D, Belliveau MJ, El Demellawy D, et al
. Pilomatrixoma of the ocular adnexa: Report of 3 cases with variations in the histopathological findings. Can J Ophthalmol 2019;54:413-6.
Wei N, Lin JY, Wang YC. The clinicopathologic observation of 64 cases of eyelid and eyebrow pilomatrixoma. Zhonghua Yan Ke Za Zhi 2013;49:997-1001.
[Figure 1], [Figure 2]