International Journal of Trichology International Journal of Trichology
 Print this page Email this page Small font sizeDefault font sizeIncrease font size
  Home | About IJT | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Online submission | Subscribe | Advertise | Contact us | Login   
Year : 2019  |  Volume : 11  |  Issue : 6  |  Page : 238-240

Scanning electron microscopy of erlotinib-induced hair changes: Pili torti et canaliculi

1 Post-Graduation Program in Health, Catholic University of Pelotas; Dermatology League, Federal University of Pelotas, Brazil
2 Dermatology League, Federal University of Pelotas, Brazil

Correspondence Address:
Prof. Hiram Larangeira de Almeida
Duque de Caxias, 250, Pelotas
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijt.ijt_98_19

Rights and Permissions

The cutaneous toxicity of the epidermal growth factor receptor inhibitors, such as erlotinib, is associated with a wide range of manifestations, such as papulopustular eruptions, xerosis, paronychia, and changes in the growth pattern of hair and nails. Hair manifestations are seen in 10%–20% of the patients. A female patient taking erlotinib for lung cancer for 8 months noticed that her scalp hair became rough on palpation and that her eyelashes were elongated. Some scalp hairs were cut and proximal and distal portions were examined in natura with scanning electron microscopy. Torsions and important grooving were seen in the proximal portions, but not in distal hair portions. Erlotinib-induced hair changes are pili torti et canaliculi.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded32    
    Comments [Add]    
    Cited by others 1    

Recommend this journal