International Journal of Trichology International Journal of Trichology
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CASE REPORT
Year : 2016  |  Volume : 8  |  Issue : 4  |  Page : 186-187

Loose anchoring of anagen hairs and pili torti due to erlotinib


1 Department of Dermatology, Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, Brazil
2 Department of Dermatology; Anatomic Pathology, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, Brazil
3 Department of Dermatology, Clinica Davila, Santiago, Chile, USA
4 Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA

Correspondence Address:
Rodrigo Pirmez
Rua Visconde de Piraja 330, Salas 1001-1003, Rio de Janeiro 22410-000, RJ
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijt.ijt_16_16

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Erlotinib is a selective epidermal growth factor receptor inhibitor utilized in the treatment of solid tumors. Cutaneous side effects, including changes in hair texture and alopecia, have been described. In this case report, we describe two patients with a new finding of loose anagen hairs and pili torti leading to nonscarring marginal and diffuse alopecia and discuss potential mechanisms underlying erlotinib-induced hair changes.


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