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ORIGINAL ARTICLE
Year : 2013  |  Volume : 5  |  Issue : 4  |  Page : 179-184

Evaluation of utility of phenol in alopecia areata


1 Department of Dermatology, Seth GS Medical College and KEM, Parel, Mumbai, Maharashtra, India
2 Department of Dermatology, LTMMC and Sion Hospital, Mumbai, Maharashtra, India
3 Department of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India

Correspondence Address:
Siddhi Chikhalkar
Department of Dermatology, OPD 117, 1st Floor, Old OPD Building, Seth GS Medical College and KEM, Parel, Mumbai - 400 012, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-7753.130390

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Background: Alopecia areata (AA) is a common hair disorder of unknown etiology and prognosis with no definitive cure. Aims and Objective: (i) To study the efficacy and immunomodulatory action of 88% phenol on hair growth on test area in AA. (ii) To study various epidemiological factors in relation to AA. Materials and Methods: A total of 50 subjects presenting with nonscarring patchy hair loss on scalp were enrolled in this prospective open label study to receive 88% phenol at 3 weekly intervals in a tertiary care hospital. Efficacy was assessed using scoring system for density, pigmentation, and texture of growing hair. Results: Texture and pigmentation of hair growth was significantly improved at 9 week, while density of hair growth showed steady improvement, which was significant from 9 week onwards. About 78% of patients showed good to excellent response while none of them showed poor response. Conclusion: 88% phenol was found to be efficacious with all patients showing hair regrowth. 88% phenol can be considered as a treatment of choice for stable AA due to its ease of application, easy availability, and low cost.


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