| ORIGINAL ARTICLE |
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| Year : 2013 | Volume
: 5
| Issue : 1 | Page : 17-21 |
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Epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children
Ramesh M Bhat, Rashmi Sharma, Anita C Pinto, Sukumar Dandekeri, Jacintha Martis
Department of Dermatology, Father Muller Medical College and Hospital, Kankanady, Mangalore, Karnataka, India
Correspondence Address:
Ramesh M Bhat
Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Kankanady, Mangalore - 575 002, Karnataka
India
 Source of Support: This study was financially supported by IADVL Loreal pigmentation research grant 2011-12, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-7753.114706
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Background: Hair pigmentation is one of the most conspicuous phenotypes in humans ranging from black, brown, and blonde to red. Premature graying of hair occurs more commonly without any underlying pathology but is said to be inherited in autosomal dominant pattern. Premature graying has been shown to be associated with a few of the autoimmune disorders. A role for environmental factors and nutritional deficiencies has also been postulated. However, to date the exact etiology of premature graying has not been established. Aim: The objective of our study was to conduct an epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children of the semi-urban area. Materials and Methods: A total of 35 cases and controls were investigated for various parameter such as Hemoglobin, total iron binding capacity, serum ferritin (S. Ferritin), serum calcium (S. Ca), serum iron (S. Iron), vitamin B12, and vitamin D3 after taking informed consent. Epidemiological and investigations correlation was established using the Chi-square and Mann Whitney test and P < 0.05 values were considered significant. Result: Among the various laboratory parameters S. Ca, S. Ferritin and vitamin D3 were low in patients with premature graying of hair. There was significant high number of vitamin D3 deficient and insufficient among the cases compared to the controls. Conclusion: According to our study S. Ca, S. Ferritin, vitamin D3 may play a role in premature graying of hair in our society. |
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