International Journal of Trichology International Journal of Trichology
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CASE REPORT
Year : 2012  |  Volume : 4  |  Issue : 2  |  Page : 83-85

Silvery grey hair: Clue to diagnose immunodeficiency


Department of Dermatology, STD and Leprosy, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India

Correspondence Address:
M S Sahana
Department of Dermatology, STD and Leprosy, Bangalore Medical College and Research Institute, Bangalore - 560 002, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-7753.96910

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Silvery hair is a common presentation of rare group of autosomal recessive disorders called Silvery hair syndromes including Griscelli syndrome (GS), Chediak-Higashi syndrome, and Elejalde syndrome. GS is characterized by a silvery grey sheen to hair, large clumped melanosomes in hair shaft, partial albinism, and variable cellular immunodeficiency. We report two cases of GS with classical clinical features and confirmatory findings by microscopic skin and hair examination.


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