International Journal of Trichology International Journal of Trichology
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Year : 2009  |  Volume : 1  |  Issue : 2  |  Page : 138-139

Immunofluoresence of the outer root sheath in anagen and telogen hair: An aid to diagnosis in pemphigus

1 Department of Dermatology, PSG Hospitals, Coimbatore, India
2 Departments of Pathology, PSG Hospitals, Coimbatore, India

Correspondence Address:
M Kumaresan
Department of Dermatology, PSG Hospitals, Coimbatore
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-7753.58558

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Desmoglein 1 and 3 are distributed in the outer root sheath (ORS) of the hair follicle. Direct immunofluoresence (DIF) pattern of ORS in cases of pemphigus resembles the DIF pattern of the perilesional skin. We performed a DIF of the anagen and telogen hair ORS in a case of pemphigus and correlated it with the DIF findings of perilesional skin. Telogen hair ORS promises to be a useful tool in performing DIF for the purpose of diagnosis and follow-up in cases of pemphigus

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