International Journal of Trichology International Journal of Trichology
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   2015| April-June  | Volume 7 | Issue 2  
    Online since July 7, 2015

 
 
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REVIEW ARTICLES
Platelet-rich plasma as a potential treatment for noncicatricial alopecias
Gkini Maria-Angeliki, Kouskoukis Alexandros-Efstratios, Rigopoulos Dimitris, Kouskoukis Konstantinos
April-June 2015, 7(2):54-63
DOI:10.4103/0974-7753.160098  PMID:26180449
Androgenetic alopecia (AGA) and alopecia areata (AA) are common hair loss disorders affecting both men and women. Despite available therapeutic options, search for new, more effective treatment is constant. Platelet-rich plasma (PRP) could be effective in promoting hair growth: (1) To present PRP and its mechanism of action in promoting hair growth and (2) to evaluate its preparation methods and its therapeutic potential in noncicatrial alopecias in a systematic review. An international bibliography search, through five databases, was conducted to find articles regarding PRP's action on hair loss. Growth factors in platelets' granules of PRP bind in the bulge area of hair follicle, promoting hair growth. In our systematic review, 14 articles matched our criteria, including 12 articles for AGA and two for AA. PRP is a potential useful therapeutic tool for alopecias, without major adverse effects. Nevertheless, due to the small number of conducted trials, further studies are required to investigate its efficacy.
  5,209 281 -
CASE REPORTS
Congenital generalized hypertrichosis, gingival hyperplasia, a coarse facies with constriction bands: A rare association
Aditya Kumar Bubna, Mahalakshmi Veeraraghavan, Sankarasubramaniam Anandan, Sudha Rangarajan
April-June 2015, 7(2):67-71
DOI:10.4103/0974-7753.160113  PMID:26180451
Congenital generalized hypertrichosis terminalis is a rare primary hypertrichotic condition, of unknown etiology presenting in the pediatric population. Though benign in nature, there is considerable psychosocial trauma attached to this, owing to the cosmetic disfigurement it produces. The association of gingival fibromatosis and a coarse facies could further worsen the cosmesis. Thus, a multidisciplinary approach involving a psychologist, a dentist apart from the dermatologist would be mandatory. We present this rare syndrome with the purpose of getting a better insight regarding the inheritance, the clinical features and the best available treatment modalities, especially the modern and novel techniques of hair removal that could be utilized to manage such individuals.
  3,964 54 -
REVIEW ARTICLES
Congenital triangular alopecia
Vincent Chun Yin Li, Paul Devakar Yesudian
April-June 2015, 7(2):48-53
DOI:10.4103/0974-7753.160089  PMID:26180448
Congenital triangular alopecia (CTA) also known as temporal triangular alopecia is a benign noncicatricial pattern of hair loss. It typically affects the frontotemporal region and rarely involves the temporoparietal or occipital scalp. It is a nonprogressive disorder that presents as a triangular, oval or lancet-shaped patch of alopecia. CTA can manifest at birth or develop later in life. The exact etiology of this condition remains unknown. Rarely, it may be associated with other disorders such as Down's syndrome and phakomatosis pigmentovascularis. The diagnosis is based on its distinct clinical appearance. Histologically, hair follicles are miniaturized and replaced by sparse vellus hair follicles. Tricoscopy using a polarized light handheld dermatoscope can be a useful diagnostic tool. CTA is often asymptomatic and remains unchanged throughout the life. No treatment is required. Surgical intervention with follicular unit hair transplantation can provide a satisfactory cosmetic result. In this paper, we have identified 126 cases of CTA in the published literature cited on PubMed between 1905 and 2015. From the available evidence, 79% of patients with CTA presented with unilateral hair loss, 18.5% with bilateral involvement and rarely, with occipital alopecia (2.5%). There was no gender predilection. These figures are entirely consistent with previously published data. Physicians should remember to consider CTA as a potential diagnosis in any patient presenting with a nonscarring alopecia in order to avoid unnecessary investigations and treatments.
  3,725 85 -
CASE REPORTS
Nail involvement in frontal fibrosing alopecia
Melanie Macpherson, Parinaz Hohendorf-Ansari, Ralph Michel Trüeb
April-June 2015, 7(2):64-66
A case of frontal fibrosing alopecia with nail involvement is presented. Nail involvement provides evidence for underlying lichen planus, and that the disease represents a rather generalized than localized process. Favorable response of the scalp condition to oral dutasteride points to an inflammatory reaction on the background of androgenetic alopecia.
  2,568 35 -
Interesting patchy alopecia
Prashant Jadhav, Vijay Zawar
April-June 2015, 7(2):74-76
DOI:10.4103/0974-7753.160116  PMID:26180453
Patchy alopecias of the scalp are frequently seen in clinical practice. We report a young man who presented with progressive patchy alopecia of the scalp, which was finally diagnosed to be due to tuberculoid leprosy. Progression of alopecia was stopped after anti-leprosy treatment was instituted. Despite high prevalence of leprosy in our country, scalp affection due to leprosy is extremely rare but important to recognize.
  2,078 44 -
Solitary trichoepithelioma of the eyelid: A clinico-pathological correlation
Adit Gupta, Mohammad Javed Ali, Dilip Kumar Mishra, Milind N Naik
April-June 2015, 7(2):80-81
DOI:10.4103/0974-7753.160119  PMID:26180455
Solitary trichoepithelioma of the eyelid is a very rare tumor, which needs to be differentiated from basaloid epithelioma and basal cell carcinoma. Diagnosis is based on clinical and histopathological examination. We present a case of an eyelid trichoepithelioma presenting as a long standing nodule with associated dermatochalasis. Although rare, this entity should be kept in the differential diagnosis of chronic, firm, nodular eyelid lesions.
  1,871 65 -
Frontal fibrosing alopecia in a male presenting with sideburn loss
Salim AlGaadi, Mariya Miteva, Antonella Tosti
April-June 2015, 7(2):72-73
DOI:10.4103/0974-7753.160115  PMID:26180452
Frontal fibrosing alopecia (FFA) is a cicatricial alopecia that affects mainly postmenopausal women. It is typically characterized by recession of frontotemporal hairline. Hair loss of eyebrows, eyelashes, axillae, limbs, and pubic area may be observed. Here, we describe a case of FFA in a male patient presenting with only localized loss of sideburns. Skin biopsy findings were consistent with lichen planopilaris. To our knowledge, this is the only reported case of FFA patient with only localized loss of sideburns.
  1,885 30 -
A rare association of childhood alopecia areata and blepharophimosis-ptosis-epicanthus inversus syndrome: Successfully treated with diphenylcyclopropenone
Soumya Jagadeesan, Pradeep Balasubramanian, Vinitha Varghese Panicker, Gopikrishnan Anjaneyan, Jacob Thomas
April-June 2015, 7(2):77-79
DOI:10.4103/0974-7753.160118  PMID:26180454
The genetic background of alopecia areata has only recently begun to get unraveled. We report the association of a case of pediatric alopecia areata with a rare genetic syndrome-blepharophimosis-ptosis-epicanthus inversus syndrome (BPES), which responded well to topical immunotherapy with diphenylcyclopropenone. In the background of increasing evidence surfacing on the genetic basis of alopecia areata, this association may be of significance.
  1,816 41 -
Woolly hair with complete atrioventricular dissociation: A rare association
V Madhu Sudhanan, Ranju Choudhary, Atishay Bhukaria, Shyam Sundar Chaudhary
April-June 2015, 7(2):82-83
DOI:10.4103/0974-7753.160120  PMID:26180456
Woolly hair is a rare congenital abnormality of structure of the scalp hair characterized by tightly coiled hair involving part or the entire scalp. There are mainly two types of woolly hair; autosomal dominant/hereditary woolly hair and autosomal recessive/familial woolly hair. We hereby report two cases of autosomal recessive/familial woolly hair from a single family associated with complete atrioventricular dissociation in one sibling, which is a very rare association and only a single case has been reported in literature with this association. This case report signifies the importance of cardiac evaluation in woolly hair and stresses the fact that hair examination is not just cosmetic but can be lifesaving.
  1,575 42 -
LETTERS TO EDITOR
Lichen planopilaris with autoimmune thyroiditis
Ujjawal Khurana, Kaushik Majumdar, Dinesh Asati, Deepti Joshi, Garima Goel, Neelkamal Kapoor
April-June 2015, 7(2):87-89
DOI:10.4103/0974-7753.160125  PMID:26180460
  1,558 47 -
EDITORIAL
"Trichotill" in the Testaments
Patrick Yesudisan
April-June 2015, 7(2):47-47
DOI:10.4103/0974-7753.160086  PMID:26180447
  1,445 47 -
LETTERS TO EDITOR
Isolated long white eyelash: An underrecognized trichologic finding
Jean Luc Bernabó, Carola Baliu, Esperanza Navarra, Juan Ferrando
April-June 2015, 7(2):84-85
DOI:10.4103/0974-7753.160121  PMID:26180457
  1,403 20 -
Unusual presentation of greying of hair
Abel Francis, S Criton, Anitta Shojan, Rashmi Philip, Mohamed Nazeer
April-June 2015, 7(2):85-86
DOI:10.4103/0974-7753.160123  PMID:26180458
  1,209 48 -
Frontal edema due to topical application of %5 minoxidil solution following mesotherapy injections
Sule Güngör, Emek Kocatürk, İlteriş Oğuz Topal
April-June 2015, 7(2):86-87
DOI:10.4103/0974-7753.160124  PMID:26180459
  813 21 -
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