International Journal of Trichology International Journal of Trichology
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   2011| January-June  | Volume 3 | Issue 1  
    Online since June 16, 2011

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Light microscopy of the hair: A simple tool to "untangle" hair disorders
Keshavmurthy A Adya, Arun C Inamadar, Aparna Palit, Ragunatha Shivanna, Niranjan S Deshmukh
January-June 2011, 3(1):46-56
Light microscopy of the hair forms an important bedside clinical tool for the diagnosis of various disorders affecting the hair. Hair abnormalities can be seen in the primary diseases affecting the hair or as a secondary involvement of hair in diseases affecting the scalp. Hair abnormalities also form a part of various genodermatoses and syndromes. In this review, we have briefly highlighted the light microscopic appearance of various infectious and non-infectious conditions affecting the hair.
  11,850 347 -
Clinical photography for trichology practice: Tips and tricks
KT Ashique, Feroze Kaliyadan
January-June 2011, 3(1):7-13
DOI:10.4103/0974-7753.82118  PMID:21769229
Clinical photography of hair disorders is an extension of photography in dermatology practice. Some points should be kept in mind while taking images of the hair and hair bearing areas in view of the reflection of light and the subsequent glare that may spoil the result. For documentation of most conditions of the hair, the same general rules of dermatological photography apply. The correct lighting is the most important aspect of clinical photography in trichology practice and can be achieved by reflected light than direct light. Special care should be taken in conditions requiring serial images to document progress/response to treatment and the most important factor in this context is consistency with respect to patient positioning, lighting, camera settings and background. Dermoscopy/trichoscopy can also be incorporated in clinical practice for image documentation.
  10,780 263 3
Adamson's Fringe, Horatio George Adamson, and Kligman's experiments and observations on Tinea capitis
Rajiv Joshi
January-June 2011, 3(1):14-19
DOI:10.4103/0974-7753.82120  PMID:21769230
Adamson's fringe is located at the upper margin of the keratogenous zone of the hair follicle where the nucleated hair shaft cornifies completely and gets converted to hard anucleated keratin. It marks also the area of complete keratinization of the cuticle and Henle's layer of the inner root sheath and the beginning of the stem of the follicle. In Tinea capitis, dermatophytic infection of the hair shaft is restricted to this zone and the fungi do not penetrate further down the infected hair in the bulb of the follicle. The fungi in Adamson's words form "a fringe of mycelium surrounding the hair shaft and project below the lower margin of the sheath of spores around the root-stem." Horatio George Adamson (1865--1955), a British dermatologist first described this phenomenon, in 1895, and this article describes Adamson's fringe with a short biography of Adamson and discusses Kligman's experiments and observations on Tinea capitis which validated the observations of Adamson and the concept of Adamson's Fringe and described the pathogenesis in Tinea capitis.
  10,345 120 -
Randomized comparison of topical betamethasone valerate foam, intralesional triamcinolone acetonide and tacrolimus ointment in management of localized alopecia areata
CM Kuldeep, Himanshu Singhal, Ashok Kumar Khare, Asit Mittal, Lalit K Gupta, Anubhav Garg
January-June 2011, 3(1):20-24
DOI:10.4103/0974-7753.82123  PMID:21769231
Background: Alopecia areata (AA) is a common, non-scarring, patchy loss of hair at scalp and elsewhere. Its pathogenesis is uncertain; however, auto-immunity has been exemplified in various studies. Familial incidence of AA is 10-42%, but in monozygotic twins is 50%. Local steroids (topical / intra-lesional) are very effective in treatment of localized AA. Aim: To compare hair regrowth and side effects of topical betamethasone valerate foam, intralesional triamcinolone acetonide and tacrolimus ointment in management of localized AA. Materials and Methods: 105 patients of localized AA were initially registered but 27 were drop out. So, 78 patients allocated at random in group A (28), B (25) and C (25) were prescribed topical betamethasone valerate foam (0.1%) twice daily, intralesional triamcinolone acetonide (10mg/ml) every 3 weeks and tacrolimus ointment (0.1%) twice daily, respectively, for 12 weeks. They were followed for next12 weeks. Hair re-growth was calculated using "HRG Scale"; scale I- (0-25%), S II-(26-50%), S III - (51-75%) and S IV- (75-100%). Results: Hair re-growth started by 3 weeks in group B (Scale I: P<0.03), turned satisfactory at 6 weeks in group A and B (Scale I: P<0.005, Scale IV: P<0.001)), good at 9 weeks (Scale I: P<0.0005, Scale IV: P<0.00015), and better by 12 weeks of treatment (Scale I: P<0.000021, Scale IV: P<0.000009) in both A and B groups. At the end of 12 weeks follow-up hair re-growth (>75%, HRG IV) was the best in group B (15 of 25, 60%), followed by A (15 of 28, 53.6%) and lastly group-C (Nil of 25, 0%) patients. Few patients reported mild pain and atrophy at injection sites, pruritus and burning with betamethasone valerate foam and tacrolimus. Conclusion: Intralesional triamcinolone acetonide is the best, betamethasone valerate foam is better than tacrolimus in management of localized AA.
  7,961 189 11
Graham-Little Piccardi Lassueur syndrome: An unusual variant of follicular lichen planus
Varadraj V Pai, Naveen N Kikkeri, Tukaram Sori, US Dinesh
January-June 2011, 3(1):28-30
DOI:10.4103/0974-7753.82129  PMID:21769233
Graham Little-Piccardi-Lassueur syndrome is a type of lichen planopilaris (follicular lichen planus) characterized by the triad of patchy cicatricial alopecia of the scalp, noncicatricial alopecia of the axilla and groin, and a follicular spinous papule on the body, scalp, or both. It is four times more common in females in the age group of 30-70 years. Only a few cases have been reported in literature wherein the disease has affected males. Herein we report a young male who presented with features of Graham Little-Piccardi-Lassueur syndrome.
  6,366 77 2
A new postulate on two stages of dandruff: A clinical perspective
Frederick Manuel, S Ranganathan
January-June 2011, 3(1):3-6
DOI:10.4103/0974-7753.82117  PMID:21769228
Dandruff (pityriasis capitis, seborrheic dermatitis confined to the scalp) is a disease that has been around for centuries despite several treatment options. Almost every day new players are entering the market with various antidandruff products, perhaps due to an increase in the incidence of dandruff all over the world. Interestingly, clinicians, especially dermatologists, gave little attention to this problem. At the end, the dandruff sufferer is puzzled by the array of antidandruff products with varied claims entering the market day by day. Why have we not achieved complete treatment success against dandruff? Is dandruff a disease or disorder? It seems that our understanding about dandruff perfectly fits into the famous saying of Albert Einstein, "as the area of light increases, so does the circumferences of darkness." Have dermatologists left dandruff unattended, only to be exploited by the personal care industry?
  6,130 226 4
Localised acquired trichorrhexis nodosa of the scalp hair induced by a specific comb and combing habit - A report of three cases
Abhay Mani Martin, P Sugathan
January-June 2011, 3(1):34-37
DOI:10.4103/0974-7753.82138  PMID:21769235
Trichorrhexis nodosa is a hair shaft disorder often encountered in clinical practice. Acquired trichorrhexis is commoner of the two types and is most often due to weathering from physical or chemical causes. We report three representative cases of localized acquired trichorrhexis encountered in our clinic attributable to a specific comb, used commonly in Kerala, a Southern state of India.
  5,688 35 3
MALDI-MS redox lipidomics applied to human hair: A first look
CD Cornellison, JM Dyer, JE Plowman, GL Krsinic, S Clerens
January-June 2011, 3(1):25-27
DOI:10.4103/0974-7753.82127  PMID:21769232
Lipids are an amazingly diverse group of biomolecules with an array of biological functions including protecting and maintaining key properties and structure. Oxidative insult in the form of UV, hydrothermal, or other damage leads to compromised lipid function and can be linked to a wide range of consumer complaints. This proof-of-principle study applied and evaluated redox lipidomic approaches for the characterization and profiling of selected lipids and their oxidation products in human hair. It was observed that cholesterol and cholesterol derivatives regions appeared to be the most susceptible to oxidative damage and this leads to further experiments, including the systematic characterization of oxidative products, and correlation of modifications with damage protocol.
  5,543 37 -
Malherbe's calcifying epithelioma (pilomatrixoma): An uncommon periocular tumor
Mohammad Javed Ali, Santosh G Honavar, Milind N Naik, Geeta K Vemuganti
January-June 2011, 3(1):31-33
DOI:10.4103/0974-7753.82134  PMID:21769234
Benign calcifying epithelioma of Malherbe or pilomatrixoma or pilomatricoma is an uncommon lesion of the periocular tissues, arising from the matrix cells at the base of the hair. In the periocular area, it usually arises from the lids and eyebrows. Pilomatrixoma has certain characteristic clinical and histopathologic features, but since it is not commonly suspected preoperatively, certain distinctive clinical features of tumor should suggest clinical diagnosis followed by histopathologic confirmation.
  4,984 43 5
Hypertrichosis due to congenital hypothyroidism
Syed Ahmed Zaki, Vijay Lad
January-June 2011, 3(1):38-39
DOI:10.4103/0974-7753.82137  PMID:21769236
  4,560 43 1
The inner root sheath and the men associated with it eponymically
Rajiv S Joshi
January-June 2011, 3(1):57-62
DOI:10.4103/0974-7753.82119  PMID:21769243
  4,129 53 2
Trichostasis spinulosa presenting as itchy papules in a young lady
Sanjay D Deshmukh, Mani Anand, Gauri E Yadav, Avinash R Joshi
January-June 2011, 3(1):44-45
DOI:10.4103/0974-7753.82126  PMID:21769241
  3,316 70 3
Congenital triangular alopecia: A close mimicker of alopecia areata
Lalit K Gupta, AK Khare, Anubhav Garg, Asit Mittal
January-June 2011, 3(1):40-41
DOI:10.4103/0974-7753.82135  PMID:21769238
  2,729 54 1
Serendipity in Trichology
Patrick Yesudian
January-June 2011, 3(1):1-2
DOI:10.4103/0974-7753.82116  PMID:21769227
  2,683 73 -
Postauricular pilar sheath acanthoma
Rupali R Bavikar, Vandana Gaopande, Sanjay D Deshmukh
January-June 2011, 3(1):39-40
DOI:10.4103/0974-7753.82136  PMID:21769237
  2,453 42 -
Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in the majority of the alopecia areata patients: Is it a primitive and pathogenic perturbation of hypothalamic-pituitary-adrenal axis?
Roberto d'Ovidio, Francesco Domenico d'Ovidio
January-June 2011, 3(1):43-44
DOI:10.4103/0974-7753.82130  PMID:21769240
  2,469 23 3
Alopecia areata - probing the deforestation
Dilip Gude
January-June 2011, 3(1):41-42
DOI:10.4103/0974-7753.82132  PMID:21769239
  1,976 69 -