International Journal of Trichology

: 2014  |  Volume : 6  |  Issue : 1  |  Page : 21--22

Three different dermoscopic view of three new cases with pilomatrixoma

Erhan Ayhan1, OC Ertugay2, R Gundogdu3,  
1 Department of Dermatology, Zile State Hospital, Tokat, Turkey
2 Department of Otorhinolaryngology, Zile State Hospital, Tokat, Turkey
3 Department of General Surgery, Zile State Hospital, Tokat, Turkey

Correspondence Address:
Erhan Ayhan
Department of Dermatology, Zile State Hospital, Tokat


Pilomatrixoma is a benign soft tissue neoplasm originated from follicular matrix of hair and is also known as Malherbe«SQ»s calcified epithelioma. Some lesions are located on the skin and are usually misdiagnosed. A small number of patients had been dermoscopically examined. In this article, three patients of pilomatrixoma who had three different dermoscopic views were evaluated and discussed in concordance with the literature.

How to cite this article:
Ayhan E, Ertugay O C, Gundogdu R. Three different dermoscopic view of three new cases with pilomatrixoma .Int J Trichol 2014;6:21-22

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Ayhan E, Ertugay O C, Gundogdu R. Three different dermoscopic view of three new cases with pilomatrixoma . Int J Trichol [serial online] 2014 [cited 2020 Jul 14 ];6:21-22
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Pilomatrixoma is a benign adnexal dermal or subcutaneous tumor [1] derived from immature matrix cells. It is first described by Malherbe and Chenantais in 1880 as a calcified tumor originating from sebaceous glands and named as pilomatrixoma by Forbis and Helwig in 1961. [1] A female predominance is known. In terms of clinical manifestation it is a single, solid, deep subcutaneous or dermal mass. It is usually localized in the head and neck region and also on upper extremities. As it has a wide variety of clinical findings, it is usually misdiagnosed. Lesions located on the skin are usually bluish or reddish in color and could morphologically vary in bullous, anetodermic or perforated masses. [2] Recently, there has been only one dermoscopic study, which had focused on diagnosis of over skin located lesions. In this article, three cases of pilomatrixoma were discussed histopathologically by using dermoscopic evaluation.


Case 1

A 67-year-old female patient has been complaining of a painless, reddish mass on her right cheek. On dermatological examination, a nodular, well-marginated, and reddish lesion of 2 cm × 2.5 cm in diameter was identified. Round yellowish spots were also seen. Dermoscopic evaluation demonstrated yellowish lobules on an erythematous background, surrounded by crown-like branching vessels [Figure 1]a]. A diagnosis of pilomatrixoma was made.{Figure 1}

Case 2

A 48-year-old male patient had a reddish nodule on his left eyebrow which had been growing slowly by 2 months. Reddish, 1 cm × 1 cm sized nodule with hairy surface was detected on the medial side of left eyebrow. Dermoscopic examination revealed erythema and bluish-white streaks like a fishing net [Figure 1]b]. These findings were in concordance with pilomatrixoma.

Case 3

A 58-year-old male patient admitted with a reddish nodule on upper left side of the nose. Physical examination revealed a reddish nodule on upper left side of nasal dorsum with an ulcerated area on its surface. Dermoscopic examination demonstrated erythema, linear irregular vessels, hairpin like vessels, comma like vessels, ulceration, and bluish areas [Figure 1]c]. A diagnosis of pilomatrixoma was made.


Dermoscopy is a diagnostic procedure focusing on evaluation of epidermal and superficial dermal structures. Although it is widely used in diagnosis of melanocytic lesions, nonmelanocytic structures have also been observed recently. First dermoscopic findings of pilomatrixoma were defined by Zaballos et al. they had reported dermoscopic results of 10 cases of pilomatrixoma in this article. Nonvascular, irregular, whitish formations (80%) and streaks (70%) were commonly observed. They assessed these findings equivalent to presence of calcification and cornified material. Reddish homogenous zones (90%), hairpin like vessels (70%), linear irregular vessels (70%) and dotted vessels (70%) were identified as vascular structures. [3] Zalaudek et al.[4] and Rosendahl et al. [5] reported two studies which comprised of keratoacanthoma and squamous cell carcinoma patients and emphasized whitish unstructured zones on dermoscopy. In addition, white rings, targetoid hair follicles, central keratin accumulations and hairpin vessels are more likely to be seen in squamous cell carcinoma and keratoacanthoma. [4],[5] White zones are also reported in Merkel cell carcinoma cases. White zones together with streaks were mentioned in two previously published articles. [6],[7] Milky pink zones, linear irregular vessels and branching vessels were also demonstrated in Merkel cell carcinoma. [6],[7] In case 1, yellowish-white zones were surrounded by crown like shaped branching vessels. These findings are also common in sebaceous hyperplasia, [8] and molluscum contagiosum. [9] Case 2 demonstrated fishing-net like bluish-white streaks. Although streaks hadn't been reported in cases out of pilomatrixoma, they could be seen in figures of some articles about Merkel cell carcinoma. [6],[7]

Linear irregular vessel and hairpin like vessel were detected in case 3. Linear irregular vessels are also commonly observed in Merkel cell carcinoma [6],[7] and melanoma. [10] Two articles about Merkel cell carcinoma which comprised of 10 and two cases also demonstrated these linear irregular vessels in all subjects. [6],[7] Hairpin like vessels on the other hand, are commonly seen in nonmelanocytic lesions such as seborrheic keratosis, keratoacanthoma and squamous cell carcinoma. [10]


Yellowish-white structures together with streaks, linear irregular vessels and hairpin like vessels are supportive dermoscopic findings of pilomatrixoma those are located on the skin however this is not enough for definitive diagnosis.


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