International Journal of Trichology

CASE REPORT
Year
: 2011  |  Volume : 3  |  Issue : 2  |  Page : 112--114

Atrichia with papular lesions


Manish Bansal, Kajal Manchanda, Sachin Lamba, SS Pandey 
 Departments of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Correspondence Address:
Manish Bansal
Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221 005, Uttar Pradesh
India

Atrichia with papular lesions (APL) is a rare autosomal recessive form of irreversible alopecia with onset at few months of age with papular keratin cysts over the body. It is associated with mutation in the Zinc finger domain of the human hairless gene on chromosome region 8p12. An eleven-year-old male presented with extensive alopecia starting at six months of age refractory to the treatment along with keratotic papules on the face and trunk. Biopsy from a papule showed mid-dermal keratin cysts and from the scalp showed few vellus follicles with no terminal hairs. The diagnosis of APL was made based upon the criteria proposed. Vitamin D-dependent rickets was ruled out as it has similar clinical presentation. Accurate diagnosis of APL is required to avoid unnecessary treatment to the patient as it is commonly misdiagnosed as alopecia universalis and treated with systemic steroids.


How to cite this article:
Bansal M, Manchanda K, Lamba S, Pandey S S. Atrichia with papular lesions.Int J Trichol 2011;3:112-114


How to cite this URL:
Bansal M, Manchanda K, Lamba S, Pandey S S. Atrichia with papular lesions. Int J Trichol [serial online] 2011 [cited 2020 Apr 8 ];3:112-114
Available from: http://www.ijtrichology.com/article.asp?issn=0974-7753;year=2011;volume=3;issue=2;spage=112;epage=114;aulast=Bansal;type=0