International Journal of Trichology International Journal of Trichology
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   Table of Contents - Current issue
Coverpage
November-December 2019
Volume 11 | Issue 6
Page Nos. 227-259

Online since Tuesday, January 14, 2020

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ORIGINAL ARTICLES  

A study of correlation of angiographic evaluation of coronary artery disease with androgenetic alopecia – TricoHeart study Highly accessed article p. 227
Vaibhav B Patil, Snehal B Lunge
DOI:10.4103/ijt.ijt_111_19  PMID:32030055
Background: Research on the association between androgenetic alopecia (AGA) and coronary artery disease (CAD) in women, with a focus on the evaluation of their angiographic association in the form of the severity of disease, has been lacking. Aim: The study aimed to evaluate the relation between CAD and AGA in women and to study their severity. Methods: This study, carried out with 438 women within 55 years of age and admitted for coronary angiography, had the case group (participants with CAD; n = 219) and control group (those without CAD; n = 219). The clinical and paraclinical data were collected after clinical history, physical examination, and review of the patients' records (family, past, and personal history of the participants). The coronary risk profiles such as diabetes mellitus, blood pressure, and serum cholesterol level were also noted, and the diagnosis of AGA was performed, and participants were grouped using the Ludwig's baldness grading system. Statistical analysis was performed by studying association between the variable using the Chi-square test (R i386.3.5.1 software). Results: In the study group, 74 (33.79%) participants were treadmill test positive, 55 (25.11%) had unstable angina, 40 (18.26%) had ST-segment elevation myocardial infarction (STEMI), and 50 (22.83%) had non-ST-STEMI (NSTEMI). In the case group, Grade II female AGA was evidenced in 38 (43.18%) participants, whereas Grade III was present in 30 (34.09%) participants. Further on, 27 patients with triple vessel disease had Grade III female AGA. Whereas, in the control group, Grade I female AGA was evidenced in 23 (65.71%) participants. Conclusion: The hypothesis that female pattern baldness is a marker for increased risk of CAD events has been studied and established as part of the present study. Further, extensive studies on the effect of other variables with a larger sample size need to be conducted.
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Tinea Capitis: Correlation of clinical aspects, findings on direct mycological examination, and agents isolated from fungal culture p. 232
Rebeca Ruppert Galarda Baptista Peixoto, Olivia Mercilene Silva Meneses, Fabiana Oliveira da Silva, Aline Donati, John Verrinder Veasey
DOI:10.4103/ijt.ijt_88_19  PMID:32030056
Background: Tinea capitis (TC) is a dermatophytosis of the scalp caused by the Trichophyton and Microsporum genera. The condition can be classified according to clinical symptoms or based on mycological presentations observed on direct examination. Treatment is best determined after isolation of the causative agent, with griseofulvin indicated for Microsporum and terbinafine for Trichophyton. Materials and Methods: This was a prospective study correlating clinical and mycological classifications with agents isolated from culture of patients seen at a tertiary hospital in São Paulo (Brazil) between May 15, 2017, and January 11, 2019. Results: A total of 23 patients were treated, comprising 19 (83%) with alopecic clinical aspect (14 [60%] trichophytic and five [23%] microsporic) and 4 (17%) with kerion celsi presentation. According to the parasite invasion at the hair shaft, 9 (40%) were endothrix and 14 (60%) were ectothrix cases. Trichophyton tonsurans was isolated from culture in 14 (60%) patients and Microsporum canis in 5 (40%) patients. A statistically significant association was found for mycological classification and agent isolated from culture (P = 0.003) with associations of the endothrix form with T. tonsurans and of ectothrix with M. canis. Conclusions: The mycological classification appears to be a valid method for suggesting the etiological agent of TC.
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CASE REPORTS Top

Diffuse alopecia areata associated with weight-loss pills p. 236
Sonia Chavez-Alvarez, AL Villarreal-Alfaro-Lopez, Osvaldo Vazquez-Martinez, Alejandra Villarreal-Martinez
DOI:10.4103/ijt.ijt_101_19  PMID:32030057
Alopecia associated with ingestion of amphetamines has been reported occasionally. These drugs may act as a triggering factor to develop diffuse alopecia. We present a case of alopecia areata possibly linked to the ingestion of amphetamines. This case may provide evidence that amphetamines can also be a cause of alopecia areata in susceptible individuals. We intend to awaken an interest in the medication history of patients presenting with sudden diffuse alopecia areata.
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Scanning electron microscopy of erlotinib-induced hair changes: Pili torti et canaliculi p. 238
Hiram Larangeira de Almeida, Débora Sarzi Sartori, Renan Pinheiro Deves, Otávio Martins Cruz
DOI:10.4103/ijt.ijt_98_19  PMID:32030058
The cutaneous toxicity of the epidermal growth factor receptor inhibitors, such as erlotinib, is associated with a wide range of manifestations, such as papulopustular eruptions, xerosis, paronychia, and changes in the growth pattern of hair and nails. Hair manifestations are seen in 10%–20% of the patients. A female patient taking erlotinib for lung cancer for 8 months noticed that her scalp hair became rough on palpation and that her eyelashes were elongated. Some scalp hairs were cut and proximal and distal portions were examined in natura with scanning electron microscopy. Torsions and important grooving were seen in the proximal portions, but not in distal hair portions. Erlotinib-induced hair changes are pili torti et canaliculi.
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Therapy-recalcitrant folliculitis decalvans controlled successfully with adalimumab p. 241
Meshal M Alhameedy, Adel M Alsantali
DOI:10.4103/ijt.ijt_92_19  PMID:32030059
Folliculitis decalvans (FD) is a rare idiopathic primary cicatricial alopecia which leads to permanent destruction of hair follicular stem cell.Staphylococcus aureus as well as autoimmunity has been implicated in the pathogenesis. Treatment options include topical antiseptics, topical and systemic corticosteroids, systemic antibiotics, isotretinoin, dapsone, hydroxychloroquine, and immunomodulators. We present the therapy-recalcitrant case of FD which is controlled successfully by subcutaneous injections of Adalimumab (Humira®) with no serious adverse events throughout the treatment.
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Alopecic and aseptic nodules of the scalp with a chronic relapsing course p. 244
Khalil I Al-Hamdi, Anwar Qais Saadoon
DOI:10.4103/ijt.ijt_106_19  PMID:32030060
Alopecic and aseptic nodules of the scalp (AANS) is a relatively new and little-known entity, and thus may possibly be underdiagnosed. This condition was first described in Japan by Iwata et al., in 1992. This disease occurs mainly in young males and is characterized by the presence of aseptic nodular scalp lesions associated with nonscarring alopecia that may resolve within 3 months. Here, we are reporting a case of AANS with a chronic relapsing course. To the best of our knowledge, this is the first case of this rare entity that has been reported in Iraq. We are urged to report this case due to the following factors: a paucity of reports in the literature (to date, fewer than 90 cases have been reported worldwide), an uncanny resemblance to other entities – especially, dissecting cellulitis of the scalp and alopecia areata – and the unusual chronic relapsing course of the disease.
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Isolated patchy heterochromia of the scalp hair: A rare entity with literature review p. 247
Priyadarshini Sahu, Surabhi Dayal, Rupinder Kaur, Jayanti Singh
DOI:10.4103/ijt.ijt_84_19  PMID:32030061
Scalp hair heterochromia involves the presence of two different colors of the scalp hair in the same individual. It may be of three types: patchy, diffuse, and segmental. Isolated patchy heterochromia of the scalp hair is a rare entity, and a very few cases have been described in the literature. Hereby, we report one such case of isolated patchy scalp hair heterochromia in a 2-year-old healthy male child with black hairs presenting with a bunch of blond hairs without any underlying abnormalities along with the literature review.
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LETTERS TO EDITOR Top

Central centrifugal cicatricial alopecia in a fair phototype patient p. 251
Diego Fernandez-Nieto, David Saceda-Corralo, Juan Jimenez-Cauhe, Cristina Pindado-Ortega, Itziar Erana, Oscar M Moreno-Arrones, Sergio Vano-Galvan
DOI:10.4103/ijt.ijt_77_19  PMID:32030062
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Giant congenital melanocytic nevus of scalp: A rare case with dermoscopic findings p. 253
Alpana Mohta, Aditi Agrawal, Arti Singh, Ramesh Kumar Kushwaha, Suresh Kumar Jain
DOI:10.4103/ijt.ijt_105_19  PMID:32030063
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Kinetics versus statistics in the analysis of therapeutic effects of mometasone and calcipotriol for the treatment of alopecia areata p. 256
Jonghoon Kang, Erin Kang
DOI:10.4103/ijt.ijt_66_19  PMID:32030064
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Proliferating trichilemmal cysts: A clinicopathological study of 14 cases p. 258
Pablo Vargas-Mora, Diego Orlandi, Claudia Morales, Irene Araya
DOI:10.4103/ijt.ijt_112_19  PMID:32030065
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