International Journal of Trichology International Journal of Trichology
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CASE REPORT
Year : 2014  |  Volume : 6  |  Issue : 1  |  Page : 25-26

The action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis


Prof. Rubem David Azulay Institute of Dermatology, Santa Casa da Misericordia, Rio de Janeiro, RJ, Brazil

Correspondence Address:
Fabiana P Zarur
203 Guimar„es Rosa Street 705, Barra da Tijuca Zipcode: 22793-620, Rio de Janeiro, RJ
Brazil
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Source of Support: None, Conflict of Interest: None


Read associated Erratum: Erratum with this article

DOI: 10.4103/0974-7753.136756

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Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation). We report a case of a patient with the complete form of the disease, and with a unique appearance of the hair shaft and eyelashes. The authors propose a possible mechanism to justify the abnormalities observed in the patient's hair shafts regarding the metabolism of prostaglandins and its relationship with the hair follicle physiological cycle.


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