International Journal of Trichology International Journal of Trichology
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REVIEW ARTICLE
Year : 2013  |  Volume : 5  |  Issue : 1  |  Page : 2-5

Desmogleins: Hair perspective


Department of Dermatology and STD, Pt. J.N.M. Medical College, Raipur, Chhattisgarh, India

Correspondence Address:
Pramod Kumar Nigam
Department of Dermatology and STD, Pt. J.N.M. Medical College, Raipur - 492 001, Chhattisgarh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-7753.114695

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Desmogleins (Dsgs) are calcium-dependent, transmembrane glycoproteins belonging to the desmosomal cadherin superfamily, which play significant roles in selective calcium ions (Ca 2+ ) dependent adhesion interactions between cell surfaces. Four subtypes of Dsg have been identified. Recent observations show the distribution of Dsgs can correlate with specific types of keratinization, anchorage of the hair, and hypotrichosis.


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