|Year : 2011 | Volume
| Issue : 3 | Page : 3
Part B – Hair Genetics, Contact Dermatitis, Drugs
|Date of Web Publication||16-Jun-2011|
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
. Part B – Hair Genetics, Contact Dermatitis, Drugs. Int J Trichol 2011;3, Suppl S1:3
Disentangling the roots of inherited hair disorders
Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Marked progress has been made in our understanding of the pathogenesis of inherited hair diseases over the past years, leading to improved classification and diagnosis of this complex group of genodermatoses. While diseases associated with excessive hair growth were recently found to be associated with large chromosomal abnormalities, hypotrichoses are usually associated with more discrete deleterious genetic defects. The deciphering of the molecular basis of inherited hypotrichoses unexpectedly revealed a pathophysiological pathway common to many of these disorders, underscoring the importance of a number of key molecules for normal and pathological development of the hair follicle, and pointing to novel molecular targets for common hair disorders.
Scalp contact dermatitis
Department of Dermatology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
Scalp contact dermatitis is uncommon and surprisingly the scalp may not be affected even if hair dye is the cause of eyelid or facial contact dermatitis. Hair dye is the most common trigger of scalp contact dermatitis. Other triggers can include anything applied to the scalp such as shampoo, conditioners, hair gels, mousse, straighteners and relaxers. We will discuss in depth the etiology and pathogenesis of scalp contact dermatitis and the approach to diagnosis and treatment.
Drugs and hair
Department of Dermatology and Venereology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Adverse drug reactions may involve the hair. Drug-induced hair disorders include hair loss (telogen effluvium, anagen effluvium, or both), excess hair growth (hypertrichosis, hirsutism) and a change in hair color or shape. A large number of drugs with different structures have been implicated in the induction of hair disorders. The lecture will review the spectrum of drug-induced hair disorders, with a focus on evidence-based data, causality, latency periods and new alerts.
Department of Dermatology, Rabin Medical Center, Petah Tikva, and Sackler School of Medicine, Tel-Aviv University, Israel.
Eighty percent of psoriatic patients report on some degree of scalp involvement, and in 25-50% of affected patients the disease presents initially on the scalp. Some clinical aspects of scalp psoriasis, the question as to whether it may cause hair loss, and the therapeutic effect of new topical preparations will be discussed. The efficacy of biologics drugs on scalp psoriasis will be reviewed as well. At last, a possible treatment algorithm will be presented.